Following structural damage and functional impairment of the muscle tissue, myofibrillar rupture and extravasation of intracellular proteins such as myoglobin, creatine kinase (CK), and lactate dehydrogenase (LDH), into the extracellular medium, trigger the local inflammatory response [47, 50,51,52]
In addition, jet fuelassociated decreases in spontaneous spiking activity observed in the cerebellum, although not reaching significance, may lend mechanistic insight into alterations in motor activity and coordination observed following jet fuel exposures
Moore KH, Murphy HA, George EM
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staggering by a few hours is also common to isolate any tolerability signal to one compound